BIOJUVE

Understanding BIOJUVE™

BIOJUVE™ uses a unique, clinically proven technology with live microbes that harnesses the power of a live strain of C. acnes defendens to optimize skin health for a wide range of anti-aging skin concerns.

How does it work?

BIOJUVE is based on our proprietary live strain of C. acnes defendens, which we call Xycrobe™ Technology. These microbial powerhouses naturally produce and deliver potent Bioessentials™ such as proteins, polypeptides, and antioxidants. As facultative anaerobes, the Xycrobes live and thrive both on the skin's surface and deep within the hair follicles, thus ensuring a healthy skin biome and balanced environment around the clock.

What is Skin Biome Care?

Traditional skincare has historically focused on skin cells, paying little to no attention to the skin's microbiome. Skin Biome Care targets skin cells while simultaneously optimizing the skin's microbiome and its environment (pH, hydration, etc.). Skin Biome Care is the most comprehensive approach to skincare.

Glossary of terms

Probiotic: a beneficial live bacterium that promotes health by producing metabolic products that create a positive skin environment. A balanced or "normal" microbiome can:

• compete with pathogenic organisms for space and nutrients,
• Protect the skin from environmental stressors (from the inside and outside).
• Strengthen the skin barrier.
• They produce vitamins, amino acids, and antioxidants that are essential for the health and vitality of the skin.
  
  

Prebiotic: a substance that provides the right food source and environment for bacteria.

Postbiotic: Metabolic products of bacteria that offer health benefits to the host.

Skin microbiome: the collection of microbes, including bacteria, fungi, archaea and viruses, that live on the skin surface and deep within the skin layers.

The skin biome encompasses the skin, its microbiome, and the environment (pH, humidity, temperature, etc.). Skin biome care is therefore the optimal way to care for the skin as a whole.

Cutibacterium acnes (C. acnes): C. acnes is the most common bacterial species found on the skin of every human being, including those who do not suffer from acne.

• formerly known as Propionibacterium acnes (P. acnes)
• a relatively slow-growing, facultatively anaerobic bacterium
• lives deep within the hair follicles and pores
• uses tallow as its primary energy and nutrient source
  
  

C. acnes defendens: a special subspecies of C. acnes associated with skin health. BIOJUVE uses a patented strain of C. acnes defendens known as Xycrobe™ Technology.

Xycrobe™ Technology: The patented Xycrobe Technology (a protected strain of C. acnes defendens called XYCM42 in the clinical study) in BIOJUVE is the first live microbe technology of its kind, delivering beneficial Bioessentials™ on and within the skin. These microbes, which we call Xycrobes, live and thrive both on the skin's surface and deep within the hair follicles, providing unprecedented access to skin cells, day in, day out, 24 hours a day.

Bioessentials™: contain proteins, fatty acids, polypeptides and antioxidants that support a healthy skin environment, combat oxidative stress factors, promote skin hydration, soothe the skin, reduce redness and balance sebum production.

Frequently asked questions about BIOJUVE

Are there any safety concerns related to BIOJUVE™ products?
No adverse events were reported in the BIOJUVE clinical study with 121 subjects.

Are these products safe for pregnant or breastfeeding patients?
Xycrobe technology contains a live, proprietary strain of a bacterium naturally found on the skin. We recommend consulting your doctor to determine if you can use BIOJUVE products during pregnancy or while breastfeeding.

How quickly can results be seen?
All endpoints measured in the BIOJUVE clinical study showed significant and continuous improvement over 8 weeks, with results already visible after one week.*

Who are the best candidates for BIOJUVE?
For anyone seeking a natural, holistic method of skin rejuvenation! Nurturing the skin biome is the optimal way to care for our skin.

Can I use other products together with BIOJUVE?
All BIOJUVE products have been formulated and tested for compatibility with the technology of living Xycrobes, ensuring that the Xycrobes can live, produce, and generate Bioessentials around the clock. To achieve the results shown in the BIOJUVE clinical study, we recommend using all five BIOJUVE products as they were used in the study. This allows the skin to benefit from the effects of the Bioessentials continuously.

Are BIOJUVE products safe for use under the eyes?
BIOJUVE products can be used around the eyes. In our clinical BIOJUVE study, we observed a significant improvement in the appearance of dark circles and puffiness under the eyes.

Is there a transition period when switching to BIOJUVE products?
It is not uncommon to experience a temporary reaction when switching topical treatments. In the case of BIOJUVE, we are restoring a healthy skin biome. Depending on the state of your skin biome and what it was exposed to before using BIOJUVE, the microbes on your skin and your skin's immune system may react to the abrupt change until equilibrium is reached. This adjustment can take several weeks. We recommend discontinuing any previous topical products for three days before starting BIOJUVE to allow your skin biome to adapt. Should you experience a temporary reaction, we recommend gradually incorporating BIOJUVE products into your regimen, starting with the nighttime regimen of Conditioning Cleanse and Living Biome Essentials Serum, and the daytime regimen of Conditioning Cleanse and a Hydrating Barrier Cream. Once your skin has become accustomed to these products, the Biome Support Complex can be added to your daytime regimen.